Taken together, these results support the more beneficial effect of telmisartan than taurinein obese rats by improving SBP, in addition to ameliorating hyperglycemia, dyslipidemia,( metabolic disturbances) and decreasing plasma ADMA but increasing kidney DDAH enzyme activities (vascular complications) at least in part, by improving insulin sensitivity and decreasing oxidative stress, suggesting the possible use of telmisartan as a protective strategy against vascular complications related to obesity. It is not known what effects taurine supplementation would have on a fetus. Telmisartan or taurine administration resulted in decreased SBP, plasma glucose, lipid profile, insulin, insulin resistance, MDA, and ADMA but increased both plasma HDL level and PON-1activity, in addition to kidney DDAH enzyme activity with more significant effect of telmisartan than taurine. Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age. Increased plasma glucose, lipid profile (except HDL), insulin, insulin resistance, MDA, and ADMA but decreased HDL, PON-1 and DDAH were also observed. Results: The high fat diet group had greater body weight and higher SBP as compared to control rats. Methods: Sixty male Wistar rats were randomly divided into six groups (n=10) for 8 weeks three groups of them received standard diet with either vehicle or taurine (3% w/v in drinking water) or telmisartan (5 mg/kg, oral) while the other three groups received high fat diet with either vehicle or taurine or telmisartan. So, this study aimed to compare between telmisartan and taurine supplementation on systolic blood pressure (SBP) in addition to some metabolic disturbances and some vascular complications in an animal model for obesity. Obesity, insulin resistance, hypertension and fatty liver, are key risk factors for vascular complications. Maha Mohamed El Batsh and Manal Mohamed El Batch Some researchers have tagged this medication as a ‘wonder molecule’ as very few supplements are beneficial for the human body as this is.Abstract Telmisartan is More Effective than Taurine in Protecting High Fat Diet Induced Obesity in Rats from Hypertension, Some Metabolic, Oxidative Stress and Vascular Complications The drug is available in tablet as well as powder form and is consumed orally. In the case of some patients, doctors may prescribe a dose that is even above 2,000 mg a day. Complications may arise in case patients taking this medication as a supplement may also suffer from kidney disease.ĭaily dosage of the drug may vary from 500 mg to about 2,000 mg. It is also prescribed as a supplements to patients who are suffering from hypertension, heart disease, a disease of the liver, cholesterol, autism, problems of the eye, diabetes and seizures.Īs per medical research this drug does not lead to any reported side effects if it is taken as prescribed by the doctor. This medication is given as a supplement to adults and children who cannot produce or produce insufficient amounts of this chemical in the body. When it comes to food the best sources of it are fish and meat. This chemical is mostly found in the heart, retina, brain and platelets. Taurine is particularly known as an amino sulfonic acid, which is a chemical that helps in building up protein in the body.

Taurine dosage for schizophrenia